3rd Edition. — Oxford University Press, 2004. — 1268 p.
The third edition of the Oxford Textbook of Rheumatology sets out to capture the excitement evident to most rheumatologists as the bench to bedsideâ concept genuinely delivers new drugs for the treatment of rheumatic diseases. Although we have endeavoured to keep the best ideas and section layout of the first two editions, the pace of change in methods of assessment, our understanding of immunopathology, and imaging have demanded many changes to this edition. Most obviously we now welcome Ferdinand Breedveld as the fifth editor. Ferdinand brings us a wealth of experience as a clinician-scientist who reflects the growing importance of Europe as the source of ideas and clinical trials in rheumatology. As in the second edition, we have had a turnover of some 25 per cent of chapter authors to try and capture the best possible selection of leaders in their field and those who deliver their chapters on time!
This third edition provides a new section on health outcomes in the rheumatic diseases ranging widely from rehabilitation to problems with sexuality and the economics of caring for patients with arthritis. The chapters on vasculitides have been significantly revised and there are new chapters on the problems of adolescence macrophage activation syndrome and management issues in patients with rheumatoid arthritis and systemic lupus erythematosus. Many chapters have sections examining the use of the new biological therapies and we have encouraged more management algorithms.
However, we do not see the need to make this textbook ever larger in size. The availability of the internet to most rheumatologists makes vast reference lists unnecessary. However, we have aimed to provide rather more than a mere shortlist of advised reading. Our authors have been asked to quote key and around 100 useful overview references per chapter.
We believe the Oxford Textbook of Rheumatology has an established place in world rheumatology and hope that this third edition will be a welcome and timely addition to the library of those training in rheumatology, established rheumatologists, and scientists interested in the subject.
Contents
Clinical presentation of rheumatic diseaseClinical presentations in different age groups
Common clinical problems
Views from different perspectives
Outcomes and issues in delivering rheumatological careOutcome assessment in rheumatology
Rehabilitation of adults
Rehabilitation of children
Rheumatic disease and sexuality
Pathophysiology of musculoskeletal diseaseGenomics and its relevance to rheumatology
Molecular abnormalities of collagen and connective tissue
Articular cartilage
Bone in health and disease
The physiology of the joint and its disturbance in inflammation
Synovial pathology
Skeletal muscle physiology and damage
Biomechanics of articulations and derangements in disease
The neurophysiology of pain
The process of inflammationCells, cytokines, and other mediators
Leucocyte trafficking in inflammation
Specific immune responses
Animal models of arthritis
Modification of inflammation
Investigation of the rheumatic diseasesAcute phase response
Biochemistry
Microbiology and diagnostic serology
Serological profile
Joint fluid
Imaging
Histopathology
Electrophysiology
The scope of rheumatic diseaseEpidemiology
Infections
Rheumatoid arthritis
Spondyloarthropathies
Arthropathies primarily occurring in childhood
Systemic lupus erythematosus
Scleroderma and related disorders in adults and children
Polymyositis and dermatomyositis
Sjogren's syndrome
Vasculitis
Overlap syndromes in adults and children
Miscellaneous inflammatory conditions
Soft-tissue rheumatism
Osteoarthritis
Crystal arthropathies
Diseases of bone and cartilage
Disorders of the spine
Miscellaneous abnormalities of connective tissue
Surgical intervention and sports medicineSurgery in adults
Surgery in children
Corticosteroid injection therapy
Sports medicine
Sports injuries