Nesterova A.P., Klimov E.A., Zharkova M. et al. Disease Pathways: An Atlas of Human Disease Signaling Pathways

Boston: Elsevier, 2020. — 1227 p.Disease Pathways: An Atlas of Human Disease Signaling Pathways is designed to fill a void of illustrated reviews about the cellular mechanisms of human diseases. It covers 42 of the most common non-oncologic diseases and illustrates the connections between the molecular causes of the disease and its symptoms. This resource provides readers with detailed information about the disease molecular pathways, while keeping the presentation simple. Pathway models that aggregate the knowledge about protein–protein interactions have become indispensable tools in many areas of molecular biology, pharmacology, and medicine. In addition to disease pathways, the book includes a comprehensive overview of molecular signaling biology and application of pathway models in the analysis of big data for drug discovery and personalized medicine. This is a must-have reference for general biologists, biochemists, students, medical workers, and everyone interested in the cellular and molecular mechanisms of human disease.Human disease pathways
Infectious diseases
Human immunodeficiency virus (HIV) and acquired immunodeficiency syndrome (AIDS)
Human T-cell leukemia virus infection and leukemia progression
Human papillomavirus infection and cancer
Diseases of the blood
Endocrine, nutritional, and metabolic diseases
Diseases of the nervous system
Diseases of the eye
Diseases of the ear
Diseases of the circulatory system
Diseases of the respiratory system
Diseases of the digestive system
Diseases of the skin and subcutaneous tissue
Diseases of the musculoskeletal system
Pathway analysis perspectives/advantages
Applications of disease pathways in biology and medicine