Chang Matthew W. (ed.) Principles in Microbiome Engineering

Wiley-VCH, 2022. — 328 p. — (Advanced Biotechnology). — ISBN 978-3-527-34725-4.Microbiomes, the communities of microorganisms that inhabit specific ecosystems or organisms, can be engineered to modify the structure of microbiota and reestablish ecological balance. In recent years, a better understanding of microbial composition and host-microbe interactions has led to the development of new applications for improving human health and increasing agricultural productivity and quality. Principles in Microbiome Engineering introduces readers to the tools and applications involved in manipulating the composition of a microbial community to improve the function of an eco-system. Covering a range of key topics, this up-to-date volume discusses current research in areas such as microbiome-based therapeutics for human diseases, crop plant breeding, animal husbandry, soil engineering, food and beverage applications, and more. Divided into three sections, the text first describes the critical roles of systems biology, synthetic biology, computer modelling, and machine learning in microbiome engineering. Next, the volume explores various state-of-the-art applications, including cancer immunotherapy and prevention of diseases associated with the human microbiome, followed by a concluding section offering perspectives on the future of microbiome engineering and potential applications. Edited and authored by leading researchers in the rapidly evolving field, Principles in Microbiome Engineering is an essential resource for biotechnologists, biochemists, microbiologists, pharmacologists, and practitioners working in the biotechnology and pharmaceutical industries.Diet‐Based Microbiome Modulation: You are What You Eat
Microbiome Engineering for Metabolic Disorders
Repurposing Microbes for Therapeutic Applications in Humans
Modulating Residence Time and Biogeography of Engineered Probiotics
Microbiome Engineering for Next‐Generation Precision Agriculture
Biological Sensors for Microbiome Diagnostics
Principles, Tools, and Applications of Synthetic Consortia Toward Microbiome Engineering
Fecal Microbiota Transplantation for Microbiome Modulation: A Clinical View
Maternal Microbiota as a Therapeutic Target
Transcription Factor‐Based Biosensors and Their Application in Microbiome Engineering