Nicknam M.H. (ed.) Ankylosing Spondylitis - Axial Spondyloarthritis: Cellular, Molecular and Environmental Factors

Springer, 2022. — 188 p. — ISBN 978-981-16-4732-1.Ankylosing Spondylitis is a chronic autoimmune disease that affects about 1-3% of the world population. This debilitating disease affecting primarily young males exerts considerable socio-economic consequences. The exact pathogenesis of AS has not yet been fully understood; therefore, novel, detailed information sources are required. This book offers cutting-edge knowledge about the molecular basic and immunological mechanisms involved in the pathogenesis of Ankylosing Spondylitis. It is one of the scarce scientific resources discussing the environmental factors triggering the disease, along with the clinical manifestations, diagnostic methods, and treatments. This book covers the most recent and reliable researches and developments about spondyloarthropathies in order to provide elaborated, integrated guidance on the molecular mechanisms of Spondyloarthropathies. It will prove helpful for rheumatologists, immunologists, biologists, geneticists, and medical science students who wish to learn more about SpAs.An Overview to Ankylosing Spondylitis and Spondyloarthropa​thies
Cells and Cytokines
Innate Immune-Related Cells and Cytokines in Spondyloarthropa​thies
Adaptive Immune-Related Cells and Cytokines in Spondyloarthropa​thies
Genes
Association of HLA and HLA-Related Genes with Ankylosing Spondylitis
Association of Non-HLA Genes with Ankylosing Spondylitis
Environmental Factors
Spondyloarthropa​thies and Gut Microbiota
Spondyloarthropa​thies and Food Intake
Spondyloarthropa​thies and Environmental Stresses