Subramanian M.A. Toxicology: Principles and Methods

2nd Edition. — MJP Publishers, 2015. — 350 p. — ISBN: 978-81-8094-078-1.The study of toxicants-their route of entry, their absorption, distribution, elimination and transformation, and their dynamics within organisms and the environment-have been clearly dealt with in this book. It provides a concise, well-balanced and technical introduction to toxicology with focus on the basic principles and concepts. It would prove to be a complete study unit for new entrants to this field. The chapter "Impact of pollutants on aquatic organisms" has been written exclusively based on the author's laboratory observations.Toxic substances.
Toxicity.
Routes of exposure of toxicants.
Absorption of toxicants.
Distribution of toxicants.
Excretion of toxicants.
Biotransformation.
Mode of action of xenobiotics.
Target-site interactions.
Combined action of toxicants.
Dose–response relationship.
Teratogens.
Carcinogens.
Mutagens.
Safety evaluation of toxicants.
Toxicity at the level of organs and organ systems.
Impact of pollutants on aquatic organisms.
Environmental toxicology.
Persistence and residual nature of toxicants.
Basics of nutritional toxicology.
Liver function tests in toxicology.
Antidotal procedures (treatment of intoxication).
Selected toxicological methods.