Waksman Ron, Serruys Patrick W., Schaar Johannes (eds.) Handbook of the Vulnerable Plaque

2nd edition. — CRC Press, 2007. — 514 p.Since publication of the First Edition, advances in the diagnosis and prevention and treatment strategies of the vulnerable plaque have necessitated this greatly expanded second edition. With several new chapters covering mainly diagnostic and treatment options, The Handbook of the Vulnerable Plaque will remain the benchmark text for all interventional cardiologists treating vulnerable patients by providing the physician with comprehensive insight into the world of the vulnerable plaque.Background epidemiology and pathology
Definition and terminology of the vulnerable plaque
Pathology of the vulnerable plaque
The molecular basics of vulnerable plaque
Platelets and the vulnerable plaque
Role of metalloproteinases in the vulnerable plaque
Oxidative stress and the vulnerable plaque
Carotid vulnerable plaque
Psychological triggers for plaque rupture
Animal models of vulnerable plaque
Biomarkers
Endothelial biomarkers of vulnerable plaque progression
Biomarkers
Epidemiology of lipoprotein-associated phospholipase A2
Invasive imaging
Angiography and the vulnerable plaque
Imaging the vulnerable plaque by ultrasound
Intravascular palpography for vulnerable plaque assessment
Diffuse reflectance near-infrared spectroscopy as a clinical technique to detect high-risk atherosclerotic plaques
Optical coherence tomography
Virtual histology
Shear stress and the vulnerable plaque
Vasa vasorum and vulnerable plaques
Intravascular magnetic resonance imaging
Intracoronary thermography: basic principles
Intracoronary thermography
Non-invasive imaging
Targeted nanoparticle contrast agents for vascular molecular imaging and therapy
Nuclear imaging of the vulnerable plaque 3
Nanoparticle-based targeted delivery of therapeutics and non-invasive imaging of unstable endothelium
Multislice computed tomography coronary plaque imaging
Magnetic resonance imaging
Systemic therapy
Influenza vaccination as a strategy to prevent cardiovascular events
Vaccination: bedside
Immunomodulation of atherosclerosis
Multifocal coronary plaque instability: evidence for a systemic inflammatory process
Stem cell therapy in heart disease
Local therapy
Photodynamic therapy
Stenting the vulnerable plaque
Clinical management
PREVAIL study
Regulatory issues of the Food and Drug Administration
Investing in vulnerable plaque