Maiti S., Sen K.K. (Eds.) Bio-Targets and Drug Delivery Approaches

Taylor & Francis Group, LLC, USA, 2017. — 582 p. — ISBN13: 9781498729994In recent years, the search for biological targets and the consequent development of targeted delivery systems have been an intensive area of pharmaceutical research. Drugs cannot exert their therapeutic effects if they do not reach their target sites in the body at the appropriate concentration and persist for a sufficient length of time. To maximize drug utilization, it is necessary to deliver drugs at the target tissue. Therefore, the design of controlled release or bioresponsive formulation, which can liberate the active constituents over a long period of time, has been proven beneficial in terms of better pharmacological performance at low doses with reduced side effects. New modes of drug administration are also under investigation to overcome the obstacles associated with biodegradation and pharmacokinetics. Most general pharmacy textbooks focus on conventional pharmaceutical formulations such as tablets, capsules, ointments, suppositories, etc.Basic Concepts in Drug Targeting
Biological Targets: Identification, Selection, and Validation
Emerging Therapeutic Targets for Diabetes
Prodrug Strategy: An Effective Tool in Drug Delivery and Targeting
Drug-Targeting Strategies to CNS Disorders
Natural Polymers in Colon Targeting: Approaches and Future Perspectives
Lymphatic Drug Targeting
New Drug Targets and Drug Delivery Strategies for Various Ocular Disorders
Bone-Targeted Drug Delivery Systems
Targeted Drug Delivery in Solid Tumors: An Overview and Novel Approaches for Therapy
Mitochondria as an Emerging Target for the Delivery of Small Therapeutic Molecules
Antisense Oligonucleotide-Mediated Target-Specific Gene Silencing: Design, Delivery Strategies, and Therapeutic Applications
Biodegradable Polymeric Carriers for Delivery of siRNA
Organic–Inorganic Nanocomposites for Biomedical Applications
Carbon Nanotube-Induced Targeted Drug Delivery
Functionalized Cyclodextrin: A Versatile Supramolecular System for Drug Delivery
Nanopolymer Scaffolds as Novel Carriers for Cells and Drugs
Bio-Targets for Polyionic Glucan Derivatives and Their Nano-Therapeutic Systems
Novel Carriers for Targeted Delivery of Herbal Medicines
Toxicological Concerns Related to Nanoscale Drug Delivery Systems