Pollard T.D. et al. Cell Biology

3rd Edition. — Elsevier, 2017. — 900 p. — ISBN: 978-0-323-34126-4The much-anticipated 3rd edition of Cell Biology delivers comprehensive, clearly written, and richly illustrated content to today’s students, all in a user-friendly format. Relevant to both research and clinical practice, this rich resource covers key principles of cellular function and uses them to explain how molecular defects lead to cellular dysfunction and cause human disease. Concise text and visually amazing graphics simplify complex information and help readers make the most of their study time.
Clearly written format incorporates rich illustrations, diagrams, and charts.
Uses real examples to illustrate key cell biology concepts.
Includes beneficial cell physiology coverage.
Clinically oriented text relates cell biology to pathophysiology and medicine.
Takes a mechanistic approach to molecular processes.
Major new didactic chapter flow leads with the latest on genome organization, gene expression and RNA processing.
Boasts exciting new content including the evolutionary origin of eukaryotes, super resolution fluorescence microscopy, cryo-electron microscopy, gene editing by CRISPR/Cas9, contributions of high throughput DNA sequencing to understand genome organization and gene expression, microRNAs, IncRNAs, membrane-shaping proteins, organelle-organelle contact sites, microbiota, autophagy, ERAD, motor protein mechanisms, stem cells, and cell cycle regulation.
Features specially expanded coverage of genome sequencing and regulation, endocytosis, cancer genomics, the cytoskeleton, DNA damage response, necroptosis, and RNA processing.
Includes hundreds of new and updated diagrams and micrographs,plus fifty new protein and RNA structures to explain molecular mechanisms in unprecedented detail.
Student Consult eBook version included with purchase. This enhanced eBook experience allows you to search all of the text, figures, images, and over a dozen animations from the book on a variety of devices.Introduction to Cell Biology
Introduction to Cells
Evolution of Life on Earth
Chemical and Physical Background
Molecules: Structures and Dynamics
Biophysical Principles
Macromolecular Assembly
Research Strategies
Chromatin, Chromosomes, and the Cell Nucleus
Chromosome Organization
DNA Packaging in Chromatin and Chromosomes
Nuclear Structure and Dynamics
Central Dogma: From Gene to Protein
Gene Expression
Eukaryotic RNA Processing
Protein Synthesis and Folding
Membrane Structure and Function
Membrane Structure and Dynamics
Membrane Pumps
Membrane Carriers
Membrane Channels
Membrane Physiology
Cellular Organelles and Membrane Trafficking
Posttranslational Targeting of Proteins
Mitochondria, Chloroplasts, Peroxisomes
Endoplasmic Reticulum
Secretory Membrane System and Golgi Apparatus
Endocytosis and the Endosomal Membrane
Processing and Degradation of Cellular Components
Signaling Mechanisms
Plasma Membrane Receptors
Protein Hardware for Signaling
Second Messengers
Integration of Signals
Cellular Adhesion and the Extracellular Matrix
Cells of the Extracellular Matrix and Immune System
Extracellular Matrix Molecules
Cellular Adhesion
Intercellular Junctions
Connective Tissues
Cytoskeleton and Cellular Motility
Actin and Actin-Binding Proteins
Microtubules and Centrosomes
Intermediate Filaments
Motor Proteins
Intracellular Motility
Cellular Motility
Muscles
Cell Cycle
Introduction to the Cell Cycle
G1 Phase and Regulation of Cell Proliferation
S Phase and DNA Replication
G2 Phase and Control of Entry into Mitosis
Mitosis and Cytokinesis
Meiosis
Programmed Cell DeathAppendix