3rd Edition. — Springer International Publishing, Switzerland, 2016. — 404 p. — ISBN: 3319283847.
Volume 5 contains clinical science and translation surveys on the circulatory system, visceral, musculoskeletal and skin. The state-of-the-art descriptions involve concepts for clinical diagnosis, stem cell and gene therapy, biomaterials for tissue replacement and pharmacological/biomolecule treatment strategies.
Biology of Tissue Regeneration (Volume 1) focuses on regenerative biology with chapters on extracellular matrix, asymmetric stem cell division, stem cell niche regulation, (epi)genetics, immune signalling, and regenerative biology in organ systems and model species as axolotl or zebrafi sh.
Stem Cell Science and Technology (Volume 2) provides an overview as classifi cation of stem cells and describes techniques for their derivation, programming and culture. Basic properties of differentiation states as well as function in human organism are illustrated, and areas of stem cell pathologies in cancer and therapeutic applications for these cells are discussed with emphasis on their possible use in Regenerative Medicine.
Tissue Engineering, Biomaterials and Nanotechnology (Volume 3) focuses the development of technologies, which enable an effi cient transfer of therapeutic genes and drugs exclusively to target cells and potential bioactive materials for clinical use. Principles of tissue engineering, vector technology, multifunctionalized nanoparticles and nanostructured biomaterials are described with regard to the technological development of new clinical cell technology. Imaging and targeting technologies as well as biological aspects of tissue and organ engineering are depicted.
Regenerative Therapies I (Volume 4) gives a survey on history of Regenerative Medicine and clinical translation including regulation, ethics, and preclinical development. Clinical state-of-the art, disease-specifi c approaches of new therapies, application technology, clinical achievements, and limitations are described for the central nervous system, head and respiratory system.
Regenerative Therapies II (Volume 5) contains state-of-the-art knowledge and clinical translation of Regenerative Medicine in the cardiovascular, visceral and musculoskeletal systems.
Blood
Vascular Regeneration Therapy: Endothelial Progenitor Cells for Ischemic Diseases
Heart
Myocardial Pharmacoregeneration
Liver
Gastrointestinal Tract and Endocrine System
Kidney
Urogenital Tract
Bone
Articular Cartilage Regeneration
Muscle, Ligament and Tendon Regeneration
Regenerative Therapies