2nd Edition. — Oxford University Press, 2012. — 1261 p. — ISBN: 978-0-19-927029-3.
Inspiring and motivating students from the moment it published, Organic Chemistry has established itself in just one edition as the student's choice of an organic chemistry text. The second edition refines and refocuses Organic Chemistry to produce a text that is even more student-friendly, coherent, and logical in its presentation than before. Like the first, the second edition is built on three principles:
An explanatory approach, through which the reader is motivated to understand the subject and not just learn the facts;
A mechanistic approach, giving the reader the power to understand compounds and reactions never previously encountered;
An evidence-based approach, setting out clearly how and why reactions happen as they do, giving extra depth to the reader's understanding.
The authors write clearly and directly, sharing with the reader their own fascination with the subject, and leading them carefully from topic to topic. Their honest and open narrative flags pitfalls and misconceptions, guiding the reader towards a complete picture of organic chemistry and its universal themes and principles.
What Is Organic Chemistry?
Organic Structures
Determining Organic Structures
Structure of Molecules
Organic Reactions
Nucleophilic Addition to the Carbonyl Group
Delocalization and Conjugation
Acidity, Basicity, and Pka
Using Organometallic Reagents to Make C-C Bonds
Nucleophilic Substitution at the Carbonyl Group
Nucleophilic Substitution at C=O with Loss of Carbonyl Oxygen
Equilibria, Rates, and Mechanisms
1H NMR: Proton Nuclear Magnetic Resonance
Stereochemistry
Nucleophilic Substitution at Saturated Carbon
Conformational Analysis
Elimination Reactions
Review of Spectroscopic Methods
Electrophilic Addition to Alkenes
Formation and Reactions of Enols and Enolates
Electrophilic Aromatic Substitution
Conjugate Addition and Nucleophilic Aromatic Substitution
Chemoselectivity and Protecting Groups
Regioselectivity
Alkylation of Enolates
Reactions of Enolates with Carbonyl Compounds: The Aldol and Claisen Reactions
Sulfur, Silicon, and Phosphorus in Organic Chemistry
Retrosynthetic Analysis
Aromatic Heterocycles 1: Structures and Reactions
Aromatic Heterocycles 2: Synthesis
Saturated Heterocycles and Stereoelectronics
Stereoselectivity in Cyclic Molecules
Diastereoselectivity
Pericyclic Reactions 1: Cycloadditions
Pericyclic Reactions 2: Sigmatropic and Electrocyclic Reactions
Participation, Rearrangement, and Fragmentation
Radical Reactions
Synthesis and Reactions of Carbenes
Determining Reaction Mechanisms
Organometallic Chemistry
Asymmetric Synthesis
Organic Chemistry of Life
Organic Chemistry Today