Xu Y., Ogarten P. (Eds) Computational methods for understanding bacterial and archaeal genomes

Imperial College Press, 2008. — 493 p.
In this book, we included a collection of cohesively written chapters on prokaryotic genomes, their organization and evolution, the information they encode, computational approaches to deriving such information, and to understanding their organization and evolution.When appropriate, we attempt to provide a comparative view of the bacterial and archaeal genomes and of how information is differently encoded in these two domains of life. This book is intended to be used as an introductory text book for a graduate-level microbial genomics and bioinformatics course as well as a reference book for researchers working in the area of prokaryotic genome studiesList of ContributorsGeneral Characteristics of Prokaryotic Genomes
Genes in Prokaryotic Genomes and Their Computational Prediction
Evolution of the Genetic Code: Computational Methods and Inferences
Dynamics of Prokaryotic Genome Evolution
Mobile Genetic Elements and Their Prediction
Horizontal Gene Transfer: Its Detection and Role in Microbial Evolution
Genome Reduction During Prokaryotic Evolution
Comparative Mechanisms for Transcription and Regulatory Signals in Archaea and Bacteria
Computational Techniques for Orthologous Gene Prediction in Prokaryotes
Computational Elucidation of Operons and Uber-operons
Prediction of Regulons Through Comparative Genome Analyses
Prediction of Biological Pathways Through Data Mining and Information Fusion
Microbial Pathway Models
Metagenomics