Springer, 2006. — 554 p.
Volume 2 of the multi-volume reference, BioMEMS and Biomedical Nanotechnology, includes contributions reporting on fundamental and applied investigations of the material science, biochemistry, and physics of biomedical microdevices with applications to Genomics and Proteomics. Topics include gene expression profiling utilizing microarray technology; imaging and sensing for gene detection and use in DNA analysis; and coverage of advanced microfluidic devices and the Human Genome Project. This volume is very well illustrated with many of the figures in color.
Contents
Application of Microarray TechnologiesElectronic Microarray Technology and Applications in Genomics and Proteomics
Gene Expression Profiling Utilizing Microarray Technology and RT-PCR
Microarray and Fluidic Chip for Extracellular Sensing
Cell Physiometry Tools Based on Dielectrophoresis
Hitting the Spot:The Promise of Protein Microarrays
Use of Electric Field Array Devices for Assisted Assembly of DNA Nanocomponents and Other Nanofabrication Applications
Peptide Arrays in Proteomics and Drug Discovery
From One-bead One-compound Combinatorial Libraries to Chemical Microarrays
Advanced Microfluidic Devices and Human Genome ProjectPlastic Microfluidic Devices for DNA and Protein Analyses
Centrifuge Based Fluidic Platforms
Sequencing the human genome: A historical perspective on challenges for systems integration
Nanoprobes for Imaging, Sensing and TherapyHairpin Nanoprobes for Gene Detection
Fluorescent Lanthanide Labels with Time-resolved Fluorometry in DNA Analysis
Role of SNPs and Haplotypes in Human Disease and Drug Development
Control of Biomolecular Activity by Nanoparticle Antennas
Sequence-dependent Rigidity of DNA: Influence on DNA-protein interactions and DNA in Nanochannels
Engineered Ribozymes: Efficient Tools for Molecular Gene Therapy and Gene Discovery.